منابع مشابه
The Kinetics of Multiple Enzyme Inhibition
The adaptive fermentation of galactose by yeast is inhibited by fluoride and azide. At sufficiently low concentrations, however, it is stimulated. From a mathematical analysis, using the known fact that fluoride inhibits the enzymes enolase and adenosinetriphosphatase, it is possible to infer the existence of such stimulation. Conditions for this effect are derived which relate the sensitivitie...
متن کاملThe Kinetics of Enzyme Mixtures
Even purified enzyme preparations are often heterogeneous. For example, preparations of aspartate aminotransferase or cytochrome oxidase can consist of several different forms of the enzyme. For this reason we consider how different the kinetics of the reactions catalysed by a mixture of forms of an enzyme must be to provide some indication of the characteristics of the species present. Based...
متن کاملThe Kinetics of Multiple Enzyme
In the course of studies on the adaptive fermentation of galaetose by yeast, the effects of a number of enzyme inhibitors on the adaptive process and the subsequent fermentation were investigated. The results of these experiments as they bear on the problem of adaptation have been discussed in a preliminary communication (1). However, one interesting point emerged in concentration curves fgr tw...
متن کاملEnzyme kinetics of multiple alternative substrates
An innovative theoretical approach that enables the complete characterisation of enzyme– substrate and enzyme–substrate–competitor reactions is generalised to systems with multiple alternative substrates. Based on the quasi-steady-state assumption, time-dependent closed form solutions are presented for cases with even, weak and mixed substrate competition. The analytic framework should facilita...
متن کاملthe kinetics of enzyme mixtures
even purified enzyme preparations are often heterogeneous. for example, preparations of aspartate aminotransferase or cytochrome oxidase can consist of several different forms of the enzyme. for this reason we consider how different the kinetics of the reactions catalysed by a mixture of forms of an enzyme must be to provide some indication of the characteristics of the species present. based...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of General Physiology
سال: 1947
ISSN: 1540-7748,0022-1295
DOI: 10.1085/jgp.30.4.367